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ITALIAN CYSTIC FIBROSIS
RESEARCH FOUNDATION

The Italian Cystic Fibrosis Research Foundation (FFC Ricerca)

The Italian Cystic Fibrosis Research Foundation (FFC Ricerca) was established in 1997 with the aims of fostering and funding scientific research into cystic fibrosis; training young researchers and healthcare personnel; contributing to the management of research laboratories through special agreements; spreading information about the disease, targeting the general public.

FFC Ricerca is approved by the Italian Ministry of University and Research (MUR) as a promoter of scientific research into the disease. The studies promoted and funded by FFC Ricerca aim at upgrading the currently available treatments to enhance the quality of life and the life expectancy of the people with CF (pwCF) and at understanding the basics of the defect that causes cystic fibrosis and providing a cure for all pwCF.

What is cystic fibrosis

Cystic fibrosis is one of the most common serious genetic diseases.
Cystic fibrosis (formerly called mucoviscidosis) is a generally serious disease, present from birth since it is caused by the alteration (mutation) in a CFTR gene.

WE ARE practical
HERE ARE OUR NUMBERS

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Research and service projects
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Millions of investments in research
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Professional researchers

THE RESEARCH PROJECTS

All research projects financed by the Foundation are divided by fields of investigation. There are two fundamental objectives on the basis of which they are selected by the FFC Ricerca Scientific Committee: to improve the treatments available, to increase the quality and length of life of patients; strike at the root of the defect that causes cystic fibrosis, to find a definitive cure.

AREA 1 Therapies to correct the underlying defect

GMRF#1/2026

Exploring the role of PKD1 in promoting CFTR stability and function at the cell surface
€ 105.000 funds raised
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€ 105.000
Goal

AREA 1 Therapies to correct the underlying defect

FFC#1/2026

Mapping proteins regulating CFTR mRNA stability to identify new therapeutic targets for nonsense mutations
€ 209.890 funds raised
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€ 209.890
Goal

AREA 2 Personalized therapies

FFC#2/2026

Evaluating the potential of phosphodiesterase inhibitors to enhance the efficacy of CFTR modulators and support personalized therapeutic approaches
€ 210.000 funds raised
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€ 210.000
Goal

NEWS

Initiatives, events, current affairs: to always be updated on the latest from the world dealing with cystic fibrosis and supporting research on the most widespread serious genetic disease.

News

World Cystic Fibrosis Day. FFC Ricerca’s initiatives: research, sport and solidarity

On World Cystic Fibrosis Day, FFC Ricerca is launching new research projects, the 24th National Campaign, the 14th Bike Tour and the third awareness week on healthy carrier test.

News

Cilia, Mucus and Mucociliary Interactions Gordon Research Conference

SAVE THE DATE: Barga (Lucca, Italy), Renaissance Tuscany Il Ciocco, February 14-19, 2027

News

Gene therapy for cystic fibrosis: new research developments

New evidence on CFTR gene correction opens perspectives for forms of cystic fibrosis that still lack effective treatments.