Developed skills and lines of research

Monica Borgatti graduated in 1999 in Pharmaceutical Chemistry and Technology from the University of Ferrara and earned her PhD in Biotechnology in 2004 from the same institution. She is currently an Associate Professor of Biochemistry in the Department of Life Sciences and Biotechnology at the University of Ferrara. Her research has focused particularly on the read-through strategy for the treatment of genetic diseases caused by nonsense mutations, including cystic fibrosis. She has published over 200 articles in international journals and six book chapters. She is also the holder of a patent[1] .

Projects funded by FFC Ricerca as Principal Investigator or as Research Manager

FFC#1/2012
The read-through approach for the treatment of cystic fibrosis caused by premature termination codons

FFC#2/2010
Novel cellular model system and therapeutic molecules for the development of a read-through approach for CF caused by stop codon mutations of the CFTR gene

Publications from FFC Research projects

Marzaro G, Guiotto A, Borgatti M et al., Psoralen derivatives as inhibitors of NF-κB/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation. Journal of Medicinal Chemistry, 2013, 56(5):1830-42

Fabbri E, Borgatti M, Montagner G, et al. Expression of microRNA-93 and Interleukin-8 during Pseudomonas aeruginosa–Mediated Induction of Proinflammatory Responses. Am J Respir Cell Mol Biol, 2014, 50(6):1144-55