Developed skills and lines of research

Alessandra Ghigo obtained her Bachelor’s degree in Biotechnology in 2005 and her Master’s degree in Molecular Biotechnology in 2007 from the University of Turin. In 2012, she earned her PhD in Biomedical Sciences and Human Oncology from the same institution, with a dissertation titled “PI3Kγ against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct Phosphodiesterases.” Since October 2014, she has been an Assistant Professor at the University of Turin.

Her research focuses on peptides, particularly a peptide derived from the PI3Kγ enzyme, which is crucial for the function of CFTR on the cell membrane.

Projects funded by FFC Ricerca as Principal Investigator or as Research Manager

FFC#11/2017
Development of a peptide derived from the enzyme PI3Kγ as a new and effective potentiator of the mutant F508del-CFTR

FFC#4/2016
Development of a PI3Kγ-derived peptide as a novel F508del-CFTR potentiator

Publications from FFC Research projects

Alessandra Murabito, Flora Pirozzi, Kai Ren, Mingchuan Li, Valentina Sala, Nancy L. Quinney, Carlo Laudanna, Martina Gentzsch, Emilio Hirsch and Alessandra Ghigo. Development of a PI3Kγ-derived peptide as a novel F508del-CFTR potentiator. The Proceedings of the 16th Italian Convention of Investigators in Cystic Fibrosis. Multidisciplinary Respiratory Medicine, 2019, 14 (Suppl 1):5