Developed skills and lines of research

Eugenio Notomista graduated in Biology in 1995 and subsequently earned a PhD in Molecular Biology. Since 2004, he has been a Researcher at the Faculty of Biotechnology at the University of Naples Federico II.
Prof. Notomista has focused his research on the structure-function relationship of proteins, protein sequence evolution and analysis, genome analysis, protein modeling, and the characterization and modeling of protein/membrane interactions. His scientific contributions are documented by 30 publications in international journals, 2 patents, 34 conference presentations, and approximately 30 citations per year.

Projects funded by FFC Ricerca as Principal Investigator or as Research Manager

FFC#8/2023
Inhalable nanoparticles delivering peptidomimetic/antibiotic combinations for local treatment of CF lung infections

FFC#18/2018
In vitro and in vivo efficacy of an antimicrobial and antibiofilm designed peptidomimetic against CF lung pathogens

FFC#12/2014
Inhalable dry powders for chemically-modified human Cationic AntiMicrobial Peptides (CAMPs): moving toward in vivo application

FFC#11/2013
Inhalable dry powders for chemically-modified human Cationic AntiMicrobial Peptides (CAMPs): moving toward in vivo application

Publications from FFC Research projects

D’Angelo I, Conte C, La Rotonda MI et al. Improving the efficacy of inhaled drugs in cystic fibrosis: challenges and emerging drug delivery strategies. Adv Drug Deliv Rev. 2014 Aug;75:92-111. doi: 10.1016/j.addr.2014.05.008. Epub 2014 May 17. 

Oliva R, Chino M, Pane K, et al. Exploring the role of unnatural amino acids in antimicrobial peptides. Sci Rep. 2018 Jun 11;8(1):8888. doi: 10.1038/s41598-018-27231-5.