Developed skills and lines of research

Alessandro Rimessi graduated in Pharmacy in 2002 from the University of Ferrara; in 2006, he obtained a PhD in Molecular Medicine from the Department of Physiopathology and Experimental Medicine of the University of Siena. Since 2009, Alessandro Rimessi has been a Researcher affiliated with the Ferrara Technopole Life Sciences Platform. His research has focused on the following topics:

study of the in vivo molecular mechanisms that influence and regulate the phenomenon of tumor maintenance.

study of the molecular mechanisms that regulate the control of cell apoptosis by the Ca2+ signal, through the use of chimeric cDNAs for the Ca2+ sensitive photoprotein aequorin;

use of digital fluorescence and confocal microscopy techniques, 3D analysis and reconstruction for the study of the role of Protein Kinase C in the regulation of oxidative stress;

biochemical applications for the identification of protein-protein interactions in the study of important calcium ion transporters;

Projects funded by FFC Ricerca as Principal Investigator or as Research Manager

FFC#20/2015
Mitochondrial quality control machinery a role in the P. aeruginosa-triggered inflammatory response in Cystic Fibrosis

Publications from FFC Research projects

Guglierame P, Pasca MR, De Rossi E, et al. Efflux pump genes of the resistance-nodulation division family in Burkholderia cenocepacia genome. BMC Microbiol, 2006 Jul 20;6:66.Rimessi A, Previati M, Nigro F, et al. Mitochondrial reactive oxygen species and inflammation: Molecular mechanisms, diseases and promising therapies. Int J Biochem Cell Biol, 2016 Dec;81(Pt B):281-293. doi: 10.1016/j.biocel.2016.06.015. Epub 2016 Jun 29.

Yoboue ED, Rimessi A, Anelli T et al. Regulation of Calcium Fluxes by GPX8, a Type-II Transmembrane Peroxidase Enriched at the Mitochondria-Associated Endoplasmic Reticulum Membrane. Antioxid Redox Signal. 2017 Sep 20;27(9):583-595. doi: 10.1089/ars.2016.6866. Epub 2017 Apr 17.