Developed skills and lines of research

Alba Silipo obtained her degree in Chemistry from the University of Naples Federico II in 2001 and was awarded a PhD in Chemistry from the same university in 2004. Since 2007, she has been a Researcher in Organic Chemistry at the Department of Organic and Biological Chemistry of the University of Naples. Her research experience began as a university student with the isolation, purification, and structural characterization of bacterial lipopolysaccharides and glycolipids. She is currently involved in the isolation and structural characterization of bacterial lipopolysaccharides and in the study of the molecular mechanisms underlying immune recognition, focusing on the interaction of proteins and carbohydrates involved in the immune response, through NMR and conformational analysis. She is co-author of over 65 publications in international journals. 

Projects funded by FFC Ricerca as Principal Investigator or as Research Manager

FFC#12/2012
Naturally occurring antimicrobials to counteract lung infections in cystic fibrosis patients: Cecropin A-Melittin (CA-M) hybrid peptides and polymixins

FFC#16/2009
In vitro and in vivo studies of novel antimicrobials targeting bacterial cytoskeleton and cell surface virulence markers in the treatment of Burkholderia cepacia complex infection

Publications from FFC Research projects

Di Lorenzo F, Silipo A, Bianconi I, et al. Persistent cystic fibrosis isolate Pseudomonas aeruginosa strain RP73 exhibits an under-acylated LPS structure responsible of its low inflammatory activity. Mol Immunol, 2015 Feb;63(2):166-75. doi: 10.1016/j.molimm.2014.04.004. Epub 2014 May 22.